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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 UY7l/zsxC3LhnfiDF2+phgb5dbHd4CcporzXPI7BHoKV7ld8N1it9A5WCti4zce3
 oiP8nuE91plDynyPjYe1Og==

<SEC-DOCUMENT>0001256071-11-000005.txt : 20110214
<SEC-HEADER>0001256071-11-000005.hdr.sgml : 20110214
<ACCEPTANCE-DATETIME>20110214191653
ACCESSION NUMBER:		0001256071-11-000005
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20110214
DATE AS OF CHANGE:		20110214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CALIPER LIFE SCIENCES INC
		CENTRAL INDEX KEY:			0001014672
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				330675808
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-58047
		FILM NUMBER:		11610740

	BUSINESS ADDRESS:	
		STREET 1:		68 ELM STREET
		STREET 2:		.
		CITY:			HOPKINTON
		STATE:			MA
		ZIP:			01748
		BUSINESS PHONE:		508-435-9500

	MAIL ADDRESS:	
		STREET 1:		68 ELM STREET
		STREET 2:		.
		CITY:			HOPKINTON
		STATE:			MA
		ZIP:			01748

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CALIPER TECHNOLOGIES CORP
		DATE OF NAME CHANGE:	19990921

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PLATINUM INVESTMENT MANAGEMENT LTD
		CENTRAL INDEX KEY:			0001256071
		IRS NUMBER:				000000000

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		C/O PLATINUM INVESTMENT MANAGEMENT
		STREET 2:		LEVEL 8, 7 MACQUARIE PLACE
		CITY:			SYDNEY AUSTRALIA 2000
		STATE:			C3
		ZIP:			00000
		BUSINESS PHONE:		61292557533

	MAIL ADDRESS:	
		STREET 1:		C/O PLATINUM INVESTMENT MANAGEMENT
		STREET 2:		LEVEL 8, 7 MACQUARIE PLACE
		CITY:			SYDNEY AUSTRALIA 2000
		STATE:			C3
		ZIP:			00000

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PLATINUM ASSET MANAGEMENT LTD
		DATE OF NAME CHANGE:	20030722
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>caliper91.txt
<TEXT>
Item 1.

(a)  Caliper Life Sciences Inc.

(b)  68 Elm Street
     Hopkinton, MA 01748

Item 2.

(a)  Platinum Investment Management Limited

(b)  Level 8, 7 Macquarie Place
     Sydney NSW 2000
     Australia
(c)  Australia
(d)  Common Stock
(e)  130872104

Item 3.
N/A

Item 4.

(a) 4,747,403
(b) 9.4%
(c) (i) 4,747,403
    (ii) 0
    (iii) 4,747,403
    (iv) 0

Item 5
No

Item 6
No

Item 7
N/A

Item 8
N/A

Item 9
N/A



Item 10
(a) N/A
(b) By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were not acquired and are not
held for the purpose of or with the effect of changing or influencing
the control of the issuer of the securities and were not acquired and
are not held in connection with or as a participant in any transaction
having that purpose or effect.



After reasonable inquiry and to the best of my
knowledge and belief, I certify that the information
set forth in this statement is true, complete and correct




</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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